Material Safety Data Sheet
Acetaldehyde, 99.5%

ACC# 91732
Section 1 - Chemical Product and Company Identification

MSDS Name: Acetaldehyde, 99.5%
Catalog Numbers: AC149510000, AC149510010, AC149510100, AC149512500, O1004-250, S79878
Synonyms: Acetic aldehyde; Acetylaldehyde; Ethylaldehyde; Ethanal.
Company Identification:
              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
75-07-0 Acetaldehyde > 99.5 200-836-8

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless liquid. Flash Point: -27 deg C.
Danger! Air sensitive. Oxidizes readily in air to form unstable peroxides that may explode spontaneously. Extremely flammable liquid and vapor. Vapor may cause flash fire. Causes severe eye irritation. Lachrymator (substance which increases the flow of tears). Causes respiratory tract irritation. May be harmful if swallowed. May cause skin irritation. May cause cancer based on animal studies. May cause lung damage. May cause central nervous system depression. May cause liver and kidney damage. Marine pollutant. Store in explosion-proof refrigerator. Hazardous polymerization may occur.
Target Organs: Blood, kidneys, central nervous system, liver, lungs, eyes, skin.


Potential Health Effects
Eye: Causes severe eye irritation. Vapors may cause eye irritation. May cause transient corneal injury. Lachrymator (substance which increases the flow of tears).
Skin: May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause central nervous system depression.
Inhalation: Causes respiratory tract irritation. May cause narcotic effects in high concentration. Exposure produces central nervous system depression. Vapors may cause dizziness or suffocation. Can produce delayed pulmonary edema. Inhalation of large amounts may cause respiratory stimulation, followed by respiratory depression, convulsions and possible death due to respiratory paralysis.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated eye contact may cause conjunctivitis. Prolonged skin contact may cause erythema (redness) and burns. Long-term inhalation studies of acetaldehyde produced laryngeal cancers in hamsters and nasal cancers in rats.

Section 4 - First Aid Measures


Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with soap and plenty of water. Remove contaminated clothing and shoes. Get medical aid if symptoms occur. Wash clothing before reuse.
Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors may form an explosive mixture with air. Use water spray to keep fire-exposed containers cool. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Extremely flammable liquid and vapor. Vapor may cause flash fire. Forms peroxides of unknown stability. Containers may explode in the heat of a fire. Will be easily ignited by heat, sparks or flame. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. Sensitivity to mechanical impact: Yes, if peroxides are formed. Closed containers exposed to heat may explode. Sensitive to static discharge.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Water may be ineffective. Do NOT use straight streams of water.
Flash Point: -27 deg C ( -16.60 deg F)
Autoignition Temperature: 175 deg C ( 347.00 deg F)
Explosion Limits, Lower:4.0%
Upper: 60.0%
NFPA Rating: (estimated) Health: 2; Flammability: 4; Instability: 2

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use water spray to dilute spill to a non-flammable mixture. Avoid runoff into storm sewers and ditches which lead to waterways. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Place under an inert atmosphere. U.S. regulations require reporting spills and releases to soil, water and air in excess of reportable quantities.

Section 7 - Handling and Storage


Handling: Ground and bond containers when transferring material. Do not breathe dust, mist, or vapor. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Handle under an inert atmosphere. Store protected from air. This product may be under pressure; cool before opening. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep from freezing. Store in a tightly closed container. Keep from contact with oxidizing materials. Keep away from strong acids. Refrigerator/flammables. Keep away from reducing agents. Do not expose to air. Store in explosion-proof refrigerator. After opening, purge container with nitrogen before reclosing. Periodically test for peroxide formation on long-term storage. Addition of water or appropriate reducing materials will lessen peroxide formation. Store under an inert atmosphere.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Acetaldehyde 25 ppm Ceiling 2000 ppm IDLH 200 ppm TWA; 360 mg/m3 TWA

OSHA Vacated PELs: Acetaldehyde: 100 ppm TWA; 180 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: pungent odor - fruity odor
pH: Not available.
Vapor Pressure: 750 mm Hg @ 20 deg C
Vapor Density: 1.52
Evaporation Rate:49.1
Viscosity: Not available.
Boiling Point: 21 deg C
Freezing/Melting Point:-123 deg C
Decomposition Temperature:> 400 deg C
Solubility: Soluble.
Specific Gravity/Density:0.7800
Molecular Formula:C2H4O
Molecular Weight:44.04

Section 10 - Stability and Reactivity


Chemical Stability: Unstable in air. May undergo autopolymerization. Forms explosive peroxides on prolonged storage and exposure to air. Polymerizes violently in the presence of traces of metals or acids.
Conditions to Avoid: Ignition sources, exposure to air, heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong reducing agents, acids, strong bases, alcohols, amines, ammonia, halogens, phenols, phosphorus, isocyanates, acid anhydrides, hydrogen sulfide, air, ketones, hydrogen cyanide, cobalt chloride, mercury (II) chlorate, mercury (II) perchlorate, trace metals.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, methane.
Hazardous Polymerization: May occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 75-07-0: AB1925000
LD50/LC50:
CAS# 75-07-0:
     Draize test, rabbit, eye: 40 mg Severe;
     Inhalation, mouse: LC50 = 23 gm/m3/4H;
     Inhalation, mouse: LC50 = 20300 mg/m3/2H;
     Inhalation, rat: LC50 = 13300 ppm/4H;
     Inhalation, rat: LC50 = 25000 mg/m3;
     Oral, mouse: LD50 = 900 mg/kg;
     Oral, rat: LD50 = 661 mg/kg;
     Oral, rat: LD50 = 1930 mg/kg;
     Skin, rabbit: LD50 = 3540 mg/kg;
.

Carcinogenicity:
CAS# 75-07-0:


Epidemiology: Inhalation, rat: TCLo = 735 ppm/6H/2Y-I (Tumorigenic - Carcinogenic by RTECS criteria - Sense Organs and Special Senses (Olfaction) - tumors).; Inhalation, hamster: TCLo = 2040 ppm/7H/52W-I (Tumorigenic - equivocal tumorigenic agent by RTECS criteria - Sense Organs and Special Senses (Olfaction) - tumors and Lungs, Thorax, or Respiration - tumors).
Teratogenicity: Oral, rat: TDLo = 4800 mg/kg (female 1-20 day(s) after conception) Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) and Specific Developmental Abnormalities - respiratory system and hepatobiliary system.; Oral, rat: TDLo = 5040 mg/kg (female 1-21 day(s) after conception) Specific Developmental Abnormalities - Central Nervous Systemand Endocrine System and Urogenital System.; Oral, rat: TDLo = 5040 mg/kg (female 1-21 day(s) after conception) Effects on Newborn - growth statistics (e.g.%, reduced weight gain).
Reproductive Effects: Intraperitoneal, rat: TDLo = 50 mg/kg (female 12 day(s) after conception) Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants).; Intravenous, mouse: TDLo = 4 gm/kg (female 6 day(s) after conception) Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants).
Mutagenicity: DNA Damage: Human, Lymphocyte = 1560 umol/L.; DNA Inhibition: Human Cells - not otherwise specified = 30 mmol/L.; Mutation test systems - not otherwise specified: = Human Cells - not otherwise specified = 30 mmol/L.; DNA Inhibition: Human, HeLa cell = 10 mmol/L.; Cytogenetic Analysis: Human, Leukocyte = 1000 ppm/72H (Continuous).; Sister Chromatid Exchange: Human, Lymphocyte = 1200 umol/L.; Mutation in Mammalian Somatic Cells: Human, Fibroblast = 5 mmol/L.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Fish: Fathead Minnow: EC50 = 30.8-37.2 mg/L; 96 Hr; Flow-through at 21.6-23.9°C (pH 7.1-7.63)Fish: Bluegill/Sunfish: LC50 = 53 mg/L; 96 Hr; UnspecifiedWater flea Daphnia: EC50 = 9000-14000 mg/L; 48 Hr; UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 =280.6-403.5 mg/L; 5,15,25 min; Unspecified No data available.
Environmental: In the atmosphere it will degrade in a matter of hours by reaction with hydroxyl radicals and photolysis. If released into water it will rapidly biodegrade and volatilize (half-life 3 hrs for a typical river). If spilled on land it will also rapidly evaporate and leach into the ground where it will biodegrade.
Physical: Log P(oct) = 0.5
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 75-07-0: waste number U001 (Ignitable waste).

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: ACETALDEHYDE ACETALDEHYDE
Hazard Class: 3 3
UN Number: UN1089 UN1089
Packing Group: I I
Additional Info:FLASHPOINT -39 C

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 75-07-0 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 75-07-0: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 75-07-0: immediate, delayed, fire, reactive.
Section 313
     This material contains Acetaldehyde (CAS# 75-07-0, > 99.5%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 75-07-0 is listed as a hazardous air pollutant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 75-07-0 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     CAS# 75-07-0 is considered highly hazardous by OSHA.
STATE
     CAS# 75-07-0 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act:
WARNING: This product contains Acetaldehyde, a chemical known to the state of California to cause cancer.
California No Significant Risk Level: CAS# 75-07-0: 90 æg/day NSRL (inhalation)

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN F+
Risk Phrases:
     R 12 Extremely flammable.
     R 36/37 Irritating to eyes and respiratory system.
     R 40 Limited evidence of a carcinogenic effect.

Safety Phrases:
     S 16 Keep away from sources of ignition - No smoking.
     S 33 Take precautionary measures against static discharges.
     S 36/37 Wear suitable protective clothing and gloves.

WGK (Water Danger/Protection)
     CAS# 75-07-0: 1
Canada - DSL/NDSL
     CAS# 75-07-0 is listed on Canada's DSL List.
Canada - WHMIS
     not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 75-07-0 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 1/11/2001
Revision #4 Date: 2/18/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.